5.氫水對代謝徵候群臨床有顯著療效之研究~(氫水)(原論文摘要翻譯)

氫水對代謝徵候群臨床有顯著療效之研究

代謝徵候群，是主要導致心血管疾病、糖尿病、肥胖、胰島素抗阻、高血壓血脂肪的重要原因，如何有效的控制是很重要的課題。

美國匹茲堡大學醫學研究中心的研究團隊應用含氫水針對代謝症候群患者的臨床實驗

Atsunori Nakao 博士與其團隊利用水鎂化合法之方式製造氫水

氫濃度 0.55-0.65毫米

化學式 Mg + 2H2O → Mg (OH)2 + H2.

總共實驗8周對受測者授予每日1.5-2公升的氫水 

結果顯示：

氫水增加了39%的SOD抗氧化酶超氧化物歧化酶 

降低了尿中43%的硫代巴比妥酸反应物（TBARS）

增加了高密度膽固醇HDL8%、降低了13%總膽固醇

研究表示，飲用氫水代表了預防綜合代謝徵候群與其治療的新策略，而鎂水化合法也是一種安全、方便、簡單的日常製造氫水方法。

Study  

of HydrogenEffectivenessRadical ResearchNutritionRich Water on Antioxidant Status of Subjects with Potential Metabolic Syndrome—An Open Label Pilot Study

Atsunori Nakao1,*, Yoshiya Toyoda1, Prachi Sharma2, Malkanthi Evans2 and Najla Guthrie2

1

Heart, Lung and Esophageal Surgery Institute, Department of Surgery, University of Pittsburgh Medical Center,  Pittsburgh, Pennsylvania, 15213, USA 2KGK Synergize, Inc., London, ON, postal code, Canada, N6A 5R8

;Received 6.11.2009??? accepted15.10.2009462820103?      Received 15 October, 2009; Accepted 6 November, 2009; Published online 24 February, 2010

Copyright © 200? Metabolic syndrome is characterized by cardiometabolic risk factors that includeSummary JCBN

obesity, insulin resistance, hypertension and dyslipidemia. Oxidative stress is known to play a major role in the pathogenesis of metabolic syndrome. The objective of this study was to examine the effectiveness of hydrogen rich water (1.5–2 L/day) in an open label, 8-week study on 20 subjects with potential metabolic syndrome. Hydrogen rich water was produced, by placing a metallic magnesium stick into drinking water (hydrogen concentration; 0.55–0.65 mM), by the following chemical reaction; Mg + 2H2O → Mg (OH)2 + H2. The consumption of hydrogen rich water for 8 weeks resulted in a 39% increase (p<0.05) in antioxidant enzyme superoxide dismutase (SOD) and a 43% decrease (p<0.05) in thiobarbituric acid reactive substances (TBARS) in urine. Further, subjects demonstrated an 8% increase in high density lipoprotein (HDL)-cholesterol and a 13% decrease in total cholesterol/HDL-cholesterol from baseline to week 4. There was no change in fasting glucose levels during the 8 week study. In conclusion, drinking hydrogen rich water represents a potentially novel therapeutic and preventive strategy for metabolic syndrome. The portable magnesium stick was a safe, easy and effective method of delivering hydrogen rich water for daily consumption by participants in the study.

Key Words: hydrogen, drinking water, magnesium, oxidative stress, metabolic syndrome

氫水的製備方法可透過1.電解，2.水與礦石反應、3.高壓灌注，選擇任一方法均可備製水中含氫之氫水，任一方法皆可並無特殊性、惟成本與時間之差異。美國、日本、韓國、中國研究中使用之氫水，均因其實驗設計使用三種方式產生氫水，水中含氫氣即為氫水，檢測方法須應用溶氫檢測儀檢測之、只要水中含氫氣即為醫學研究所定義之氫水。

論文來源：http://image.sciencenet.cn/olddata/kexue.com.cn/upload/blog/file/2010/3/2010312194758308365.pdf

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